Marking its 27th year of bestowing transformative research grants on young scientists, the Brain & Behavior Research Foundation (formerly known as NARSAD, or the National Alliance for Research on Schizophrenia and Depression) announced $11.8 million in 200 new, two-year grant awards, including $719,701 in new grants to 12 Harvard researchers.The foundation has awarded 3,497 two-year research grants to young investigators since the inception of its NARSAD Grants program in 1987. This $204.4 million investment in early career scientists’ bold, outside-the-box research ideas has reached across the world to 33 countries in an unprecedented effort by a privately funded philanthropy.Harvard has been a major beneficiary of Brain & Behavior Research Foundation research support, receiving approximately $22 million to 258 grantees since 1987.“Harvard University is known throughout the world as one of the great centers for neuroscience and psychiatric research,” said Jeffrey Borenstein, the president and CEO of the Brain & Behavior Research Foundation. “We are proud to support these brilliant scientists and their cutting-edge research to improve the lives of those with mental illness.”The 2013 Harvard grant recipients are:Roee Admon, McLean Hospital, will investigate neural networks responsible for acute reduction of positive mood in patients with depression, with the aim of guiding selection of treatments for individual patients as well as identifying those at risk for depressive disorders.Hannah E. Brown, Massachusetts General Hospital, is exploring the gene variant MTHFR, important for folate processing and DNA expression. She will compare gene expression in people with schizophrenia who have different variants of the gene.Joshua W. Buckholtz, Department of Psychology, is seeking to develop new means for treating the impulsive behavior that is a hallmark of bipolar disorder, addiction, attention deficit hyperactivity disorder, and personality disorders.Erin C. Dunn, Massachusetts General Hospital, will examine the interplay of genes and environment in depression, seeking to identify the relationship between genes, exposure to adversity, and functioning.Mei-Hua Hall, Harvard Medical School, will evaluate the effects of cognitive remediation training intervention for people with depression to guide further improvement of the treatment.Christopher Harvey, Harvard Medical School, will apply advanced microscopy methods to measure the flow of information between two brain areas — the prefrontal cortex and the posterior parietal cortex — thought to be central to cognitive processing, often impaired in schizophrenics.Avram Holmes, Harvard Medical School, will build upon his recent identification of a biological marker of brain dysfunction in bipolar disorder and explore whether there is similar dysfunction in major depressive disorder.Jodi Lukkes, McLean Hospital, is exploring gender-dependent increased vulnerability in adolescent girls to depressive and anxietylike disorders, and will investigate a potential link between estrogen, social stress, and alterations in stress-related brain regions during adolescent development.Lauren V. Moran, Massachusetts General Hospital, seeks to identify a biological marker for nicotine craving in schizophrenia patients, following up on findings that the connection between two regions of the brain decreased in nicotine addiction shows greater impairment in smokers with schizophrenia.Demetrio Sierra, Massachusetts General Hospital, aims to shed light on causes underlying addiction and obsessive-compulsive disorder by determining if nonhuman primates show an anatomical segregation of prefrontal cortex subregions in aversive and rewarded behaviors.Michael Treadway, McLean Hospital, will test the theory that inflammation is an underlying cause of major depressive disorder by measuring neuroinflammation in simultaneously acquired positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) brain scans.Anne Venner, Beth Israel Deaconess Medical Center, will explore the role of serotonin in the regulation of rapid eye movement (REM) sleep to determine if there is a link between selective REM sleep manipulation and the development and improvement of major depression.
FacebookTwitterLinkedInEmailPrint分享The Guardian:One of the largest lithium-ion batteries in the world is planned for Victoria after the renewable energy company Neoen won a contract to build it near the regional city of Geelong.If constructed as promised, the battery will have a power capacity of 300 megawatts and a storage capacity of 450 megawatt-hours, making it more than twice the size of the battery at Hornsdale, South Australia, which was the biggest in the world when it began operating in 2017.Like the Hornsdale facility, the Geelong battery will be built using Tesla equipment. The Victorian energy and climate change minister, Lily D’Ambrosio, said it would be installed near Moorabool Terminal Station and would be ready for the 2021-22 summer.It has been scaled back since it was first flagged in April when it was expected to be 600MW and cost $300m. While among the largest batteries in the world, it is smaller than batteries planned in California and New York.D’Ambrosio said it would improve the reliability of the power grid as ageing coal-fired power stations became less reliable and the state increased its reliance on wind and solar power. The Andrews government aims to source 40% of the state’s electricity from renewable energy by 2025, and 50% by 2030.She said consumers would pay for the use of the battery through their power bills, but suggested it would lead to a reduction in wholesale energy prices so that Victorians were charged less for electricity. Independent analysis found that Victorians would receive $2 in benefits for every $1 invested in the battery, she said. Energy consultancy Aurecon found the Hornsdale Power Reserve saved consumers $116m in 2019.[Adam Morton]More: Victoria plans 300MW Tesla battery to help stabilise grid as renewables increase French developer Neoen to build 300MW/450MWh battery storage unit in Australia
Population: 60,709Public lands: Paris Mountain State Park, Table Rock State Park, Caesars Head State Park, Jones Gap State ParkOutdoor highlights: Swamp Rabbit Trail, Falls Park, Foothills Trail, Raven Cliff Falls
By Gustavo Arias Retana/Diálogo May 18, 2020 Uncertainty prevails in Venezuela as COVID-19 spreads, not only due to the health system’s inability to face the pandemic, but also because official data are not trustworthy, and those who question them risk being detained.“You cannot trust the figures that the Nicolás Maduro regime provides. His administration has a history of lying to the people to obtain political advantages,” Mariano de Alba, a U.S.-based Venezuelan lawyer who specializes in international law and international relations, told Diálogo. “There are inconsistencies in the information reported, such as contradictory statements between state spokespersons regarding the number of cases, and persecution against journalists who publish truthful information independently.”In an attempt by the regime to hide the pandemic’s real figures, authorities arrested reporter Darvinson Rojas, accusing him of “hate speech” and “criminal incitement.” He was detained on March 21 and released on April 2, Amnesty International reported on its website. The Venezuelan National Press Workers’ Union reported via Twitter that, on March 24, authorities arrested Beatriz Rodríguez, head of the La Verdad de Vargas newspaper of La Guaira state. She was taken from her home to the prosecutor’s office for questioning about the publication of a case related to the pandemic that the newspaper had confirmed.“There is more than censorship in Venezuela. There is an explicit warning that the Ministry of Health is the only authorized institution to report figures of infected and deceased patients and any other figures,” José Ricardo Thomas, professor at the Central University of Venezuela, told Diálogo. “Going against that warning means capture, prison, or worse.”“The dictatorship has used the emergency and the pandemic to continue its persecution. In order to conceal information, they harass those who are doing their best to help our people,” Venezuelan Interim President Juan Guaidó said on Twitter.No investment in hospitalsCensorship and unproven information add to the general crisis that the Venezuelan health system is experiencing, due to the COVID-19 pandemic, the lack of doctors and supplies, and the Maduro regime’s poor management.“The Venezuelan health system is in critical condition due to the lack of public investment. There is a lot of corruption, and the regime does not prioritize health at all,” De Alba said. “In hospitals, basic services such as water, disinfectants, and the most basic supplies for patient checkup and treatment, such as alcohol and gauze, etc., are practically non-existent.”The 2019 National Hospital Survey of Venezuelan organization Doctors for Health indicated that of the 40 hospitals surveyed, 78 percent reported water scarcity, while 63 percent reported power failures, with an average of 342 outages per month — 164 people died as a result. From 2018 to 2019, the number of beds available for patients dropped from 15,600 to 8,700, the survey shows.“In recent years [in Venezuela], the government invested only in primary care modules, designed to ideologically reach the poorest, most vulnerable sectors of the country,” Thomas says. “Basically, there were Cuban doctors, comprehensive community doctors who worked in neighborhoods putting communist ideas in people’s heads; so that was their primary investment. In addition, the people appointed to head public hospitals are party officials with no hospital management training.”“The dictatorship is facing the consequences of its lies. They have underestimated the people, thinking that repression and fear can contain the inevitable,” Guaidó said.
11th Circuit Judicial Conference slated 11th Circuit Judicial Conference slated The Judicial Conference of the U.S. 11th Circuit will take place on May 12-14 at the Westin Diplomat Resort in Hollywood.The conference is being convened by the judges of the 11th Circuit to consider the business of their respective courts (the court of appeals, and the district and bankruptcy courts in Alabama, Florida, and Georgia) and to advise means of improving the administration of justice within the circuit.A limited number of spaces on a first-come, first-served basis are available to any attorney admitted to practice before the court of appeals or any of the district courts of the 11th Circuit who wishes to attend. If an attorney is interested in attending this conference, he or she should write to Circuit Executive Norman E. Loller, at 56 Forsyth Street, N.W., Atlanta, GA 30303, or send an e-mail note to [email protected] mail, conference registration information will be provided, describing the conference hotel accommodations, room charges, and the substantive and social programs. Preview information concerning the conference may be accessed on the Internet at www.cal1.uscourts.gov/JudConf. Individuals must register with the circuit executive for attendance at CLE events prior to arrival at the conference.The conference registration fee is $210 and must be received in the circuit executive’s office prior to April 20. April 15, 2005 Regular News
Allegheny County, which includes Pittsburgh, expects to report its outstanding mail votes by the end of Wednesday. Other Democratic enclaves, including Philadelphia and its suburban counties, are expected to report in the next one to three days. As of Wednesday morning, more than half of the ballots in Philadelphia had still not been counted.Looming over the counting, however, are multiple lawsuits filed by Republicans at both the county and statewide level, questioning the process by which voters were notified of issues with mail in ballots and allowed to cast provisional ballots. Hearings are scheduled in both Montgomery County and at the state level on Wednesday.At a news conference on Wednesday, Gov. Tom Wolf reiterated that election officials would count every ballot remaining.- Advertisement – PITTSBURGH — As Pennsylvania continued to count an estimated 1.4 million outstanding mail-in ballots on Wednesday, Democrats were confident that the results would skew heavily to Joseph R. Biden Jr. and ultimately deliver him a narrow victory over President Trump, whose legal team was descending on the state to mount challenges in court.Mr. Trump holds a 542,000-vote lead with 78 percent of the estimated total votes reported. Elections offices in the state’s populous, Democratic-leaning cities and suburbs were only partway through tabulating and reporting the bulk of mail ballots.- Advertisement – “Pennsylvania will have a fair election, and that election will be free of outside influences,” Mr. Wolf said. “I will vigorously, and we all will vigorously, defend against any attempt to attack that vote in Pennsylvania.” – Advertisement – “The distance now is 540,000,” he added. “So Biden probably wins the state by roughly 100,000.’’- Advertisement – So far, Mr. Biden has won nearly four in five of the mail votes reported, a reflection of the president’s monthslong disparagement of mail ballots, which led to far fewer Republicans voting by mail than Democrats than Republicans.If the unreported votes follow the same pattern, said Rich Fitzgerald, the Democratic county executive of Allegheny County, “Joe Biden would probably pick up 1,050,000 voters, Donald Trump would pick up 350,000, for a net gain for Joe Biden of about 700,000 votes.’’
Cilaos Emery fell on his last race over fences at Leopardstown in February, after which connections put him back over the smaller obstacles. Following success in the Red Mills Trial Hurdle at Gowran, Cilaos Emery was supplemented for the Champion Hurdle, finishing fourth to Epatante.“When he fell on his prep run for the Champion Chase, owner Luke McMahon took the decision that the Champion Hurdle looked wide open and chanced that,” said Patrick Mullins, assistant to his father.“I think they got their money back for finishing fourth, but we are keen to go back over fences again.- Advertisement – – Advertisement – Mullins junior said: “He was in great form last season. He won on the last day before lockdown in Clonmel.“I rode him in the Coral Cup where he ran a very good race. We dropped out in a pace which was slow. He finished sixth, but he could have finished closer on a different day.“He’s a high-class horse as well so it would be no surprise if he caused an upset.”Kemboy, who won this race in 2018, was withdrawn at the 48-hour final declaration stage.The three-time Grade One winner could reappear later this month ahead of his main early-season objective, the Savills Chase at Leopardstown over Christmas.“All is well with him. There are a few other races coming up in the next fortnight he could go for, but all is good with him. Willie has a few different races in mind,” said Mullins.“We’ll aim everything at Christmas, but it would be great to get a run in beforehand.”Of the four horses that take on the Mullins pair, Gordon Elliot’s Alpha Des Obeaux and the Joseph O’Brien-trained Mortal are owned by Gigginstown House Stud. Noel Meade’s Snow Falcon and Henry de Bromhead’s Paloma Blue complete the sextet.Elliott’s Shattered Love, wearing the Gigginstown colours, attempts to repeat last year’s victory in the T.A. Morris Memorial Irish EBF Mares Chase.The five runners include Jessica Harrington’s Magic Of Light, runner-up in the 2019 Randox Health Grand National.The Mullins stable is represented by Cabaret Queen, fresh from her last-gasp victory in the Kerry National at Listowel.“She’s been in great form since her win at Listowel,” said Mullins.“Obviously on ratings she needs to improve a little bit again, but it’s a very competitive race. Hopefully she has the advantage of being hard fit on her side. Maybe that will bring things in her favour.” Cilaos Emery tries two and a half miles for the first time as the Willie Mullins-trained gelding makes his seasonal debut in the Clonmel Oil Chase at the County Tipperary course on Thursday.The eight-year-old was fourth on his only previous attempt at the trip in the Hatton’s Grace Hurdle in 2017 behind Apples Jade, but has stuck to around two miles under both since codes since then.- Advertisement – “Ruby (Walsh) felt going up to two and a half miles might help him. He had been a very keen horse in his younger days, but he seems to settle much better now so we’re hoping that two and a half won’t pose any problem.“We’re expecting a big run.”The Closutton yard is also represented by Bachasson in a bid to win the race for a sixth time since 2013.- Advertisement –
Wolf Administration Reacts to Proposed EPA Cuts, Noting Immediate and Devastating Effects if Enacted Environment, National Issues, Press Release Harrisburg, PA – In a letter to Environmental Protection Agency (EPA) Administrator Scott Pruitt, Pennsylvania Department of Environmental Protection (DEP) Acting Secretary Patrick McDonnell outlined what the impacts of substantial cuts to the EPA would mean for the citizens and business of Pennsylvania.“These budget cuts do not reduce any of the responsibilities that DEP has to the people of Pennsylvania, but does decrease the resources available to fulfill those responsibilities,” said McDonnell in the letter. “These cuts, if enacted, would harm businesses seeking permits, and harm residents’ clean water, air, and land.”The letter outlined impacts from proposed cuts, including reductions to safe drinking water inspections, sewage and industrial wastewater inspections, brownfield redevelopment, and eliminate funding for radon protection, a problem that plagues Pennsylvania homes.In addition, the proposed budget would eliminate funding to restore the waterways, like the Susquehanna River, that feed into the Chesapeake Bay. Pennsylvania has recently made tremendous strides in improving local water quality through this program, as acknowledged by the EPA.“Pennsylvania has benefited from a long partnership with the federal government to address environmental concerns, which has resulted in great improvements to the health, quality of life, and economic prosperity of Pennsylvania residents,” said McDonnell. “We urge the Trump administration not to turn its back on those very federal-state partnerships that have produced these many benefits.”The full text of the letter is available below: March 16, 2017 SHARE Email Facebook Twitter
The launch ceremony of Shanti Sagar 18 – an 8,000m³ standardized trailing suction hopper dredger (TSHD) – took place today at Royal IHC’s shipyard in Krimpen aan den IJssel, the Netherlands.This is the second of two Beagle 8 TSHDs for Adani – the first (Shanti Sagar 17) was launched in March 2017.Each Beagle 8 is equipped with IHC’s Trailspeed Controller (TSC) and Eco Pump Controller (EPC).Developed in-house, the TSC ensures a constant speed while dredging, which leads to higher average production results and greater levels of consistency. The EPC reduces excessive cavitation as well as wear and tear, and fuel consumption, IHC said.Easy operation will be facilitated by the Intuitive Hopper Control Chair (IHCC). The ergonomic chair is equipped with controls in the armrests and enables the operator to have complete command of the dredging process.[mappress mapid=”24258″]
STX France AS has lowered the third and final block of the offshore substation topside, being constructed for the Arkona offshore wind farm, onto a transportation barge in the drydock of the company’s yard in St. Nazaire.At the offshore construction site in the Baltic Sea, the four piles for the offshore substation’s jacket foundation have been installed, the company’s spokesperson said.Weighing over 5,000 tons and as tall as a 5-floor apartment block, the offshore substation will form the centerpiece of the 385MW Arkona offshore wind farm, currently under construction by E.ON together with its partner Statoil off the coast of the German island Rügen.Arkona will comprise 60 6MW Siemens turbines scheduled for commissioning in 2019. The offshore platform will be used simultaneously by the Arkona wind farm and the power grid operator 50Hertz.The Arkona substation will collect the power generated by the wind farm’s turbines and transfer it to 50Hertz’s onshore substation in Lubmin via the 93-kilometre Ostwind 1 cable system.The offshore substation will be transported by sea along the French Atlantic coast to the Baltic. The two-week journey to the installation site is expected to take place in early 2018.