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Hereditary Breast Cancer Are You at Risk

Hereditary Breast Cancer Are You at Risk

first_img Related Items: Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, TCI, November 8, 2016 – For about five to ten percent of women diagnosed with breast cancer, hereditary factors are the root cause. In fact, having a first-degree (mother, sister, daughter) relative with breast cancer, increases the potential that you are carrying a mutated breast cancer gene.   And, women who inherit a gene mutation have a much higher risk of developing breast cancer.A gene can often harbor an abnormality that changes how the cell works or responds to its environment. According to Sara Carroll, genetic counselor at Cleveland Clinic Florida, “the most common causes of hereditary breast cancer include mutations in the BRCA 1 and BRCA 2 gene.”  There are other hereditary causes of breast cancer, but these are the most prevalent. These genes can be inherited from either parent.BRCA genes help to correct DNA damage. In people with a mutation in BRCA1 or BRCA2, the ability to repair damage is impaired and can sometimes lead to breast cancer.  This suggests an estimated 87% lifetime risk of developing breast cancer, which begins to steeply rise at the age of 30. The risk of developing breast cancer by the age of 50 is approximately 50%.There are several factors that can suggest the possibility that hereditary breast cancer runs in your family. You should be concerned if:There is both breast and ovarian cancer in your family.Diagnosis of breast cancer has occurred before age 50.Diagnosis of bilateral breast cancer (cancer in both breasts).Ask about genetic counseling if you are concerned, or call for a risk assessment appointment if you are unsure. High-risk women can be tested to screen for mutations in the BRCA genes. “Genetic testing can be beneficial in determining whether a cancer diagnosis was random or the result of an inherited mutation,” says Ms. Carroll.  This is valuable information, as there may also be an increased risk for other cancers as well.  Your family members will also benefit from discovering whether a hereditary risk exists.At the genetic counseling visit, a personal and detailed family medical history will be obtained.  Depending what your hereditary risk factors are, we can determine whether or not genetic testing is appropriate, and which genetic changes to assess.  Genetic testing involves a blood test, and the results are typically known in a few weeks. Hereditary risk assessment and genetic testing have become tools in the personalization of breast cancer treatment, by providing a basic understanding of the structure and function of genes at a molecular level. This knowledge allows the best clinical management to be determined.  In some instances, additional breast cancer risk management options may be necessary.  Tell your doctor about your family history of breast cancer and discuss whether that history might support the consideration of changes to your care.The Breast Center at Cleveland Clinic Florida is fully accredited by the National Accreditation Program for Breast Centers (NAPBC), a designation given to centers that are committed to providing the highest quality breast care. The breast cancer team provides the most up-to-date information on the genetic components of breast cancer, and offers predictive testing for family members who may have inherited a specific genetic mutation.“Understanding the increased genetic risk enables you to evaluate your options in advance.  Working with our breast cancer care team, you can create a personalized plan, designed to prevent or detect cancer at an earlier and more treatable stage,” states Ms. Carroll.  Women can be empowered to make important health decisions, armed with the knowledge of their genetic breast cancer risk.last_img read more

Stagnito Acquires BtoB Media Group

first_imgStagnito Media has acquired Zweig White Information Services’ media group, including CE News and Structural Engineer magazines. Stagnito is backed by Chicago-based private equity firm Cardinal Growth, which counts Zweig White in its portfolio of investments. Financial terms of the transaction, if any, were not disclosed.According to Stagnito president and CEO Harry Stagnito, the acquisition fits within the company’s goal of launching and acquiring media properties in the industrial engineering, architecture, construction and infrastructure industries, “both in the private and public sectors.”Previously, Harry Stagnito served as chief executive of Stagnito Communications, which was sold by Ascend Media to BNP Media in 2007 as part of Ascend’s estimated $30 million divestiture of its professional services division.last_img read more

Wilmingtons Carpenters Local 339 Donates 500 To Helmets To Hardhats Veteran Group

Wilmingtons Carpenters Local 339 Donates 500 To Helmets To Hardhats Veteran Group

first_imgWILMINGTON, MA — In recognition of Veteran’s Day, Massachusetts building trades unions, including Wilmington-based Carpenters Local 339, honored local veterans this week and raised more than $50,000 for life-changing career pathways program, Helmets to Hardhats.Helmets to Hardhats is a national nonprofit that connects National Guard, reserve and transitioning active-duty military members with meaningful, family-sustaining careers in the union building trades. Carpenters Local 339 donated $500 to the group.The Massachusetts Building Trades Council is a longtime supporter of the program, which has placed more than 575 military veterans in union construction jobs statewide.“We are so proud to support Helmets to Hardhats in providing career opportunities for our valued veterans. With these donations, we want to thank these courageous men and women for their service and send a clear message that there is a place for them with our unions,” said Frank Callahan, president of the Massachusetts Building Trades Council.The Massachusetts building trades unions represent the largest workforce in the state, and they’re focused on creating middle-class employment opportunities for families across the commonwealth, including for returning veterans. 75,000 men and women have great jobs and benefits with the union building trades, and nearly a quarter of a million children, spouses, and workers are covered by their high-quality union health plans. And through Build a Life and Building Pathways, the unions are creating new avenues of economic opportunity for women and people of color so that everyone can benefit from well-paying careers in the union construction trades.Helmets to Hardhats Executive Director Darrell Roberts recognized the generosity of the building trades unions and union contractors.“Thanks to the generous contributions of the Massachusetts building trades unions and union contractors, we’re able to ensure that our returning veterans have meaningful, well-paying careers in the union building trades. Their support has allowed us to do even more to support the commonwealth’s bravest,” said Roberts.Organizers attributed much of the partnership’s success to its focus on creating new employment opportunities, and ongoing career advancement, through extensive training. The Massachusetts building trades unions spent $48 million last year alone to ensure workers at every phase of their career had free hands-on training.(NOTE: The above press release via Carpenters Local 339.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedSTUDENT SPOTLIGHT: Wilmington’s Meagan Pennie Receives Scholarship From Sheet Metal Workers Local 17In “Education”WASHINGTON TO WILMINGTON: Senator Markey Says FCC Vote Imperils Community TelevisionIn “Government”Wilmington’s iPods For Wounded Veterans Travel To Arizona, Partner With Teamsters To Give Gifts To VeteransIn “Community”last_img read more

MoviePass reportedly changed passwords to keep users from ordering tickets

first_img Formerly known as the Google Home Hub, Google’s Nest Hub packs a wealth of Google Assistant goodness into a 7-inch screen. At $59, this is within a buck of the best price we’ve seen. It lists for $129 and sells elsewhere in the $89-to-$99 range.This is one item of many available as part of eBay’s Labor Day Sale (which, at this writing, doesn’t specifically mention Labor Day, but that’s how it was pitched to us). An Echo Dot makes a fine match for any Fire edition TV, because you can use the latter to say things like, “Alexa, turn on the TV.” Right now, the 24-inch Insignia Fire TV Edition starts at just $100, while the 32-inch Toshiba Fire TV Editions is on sale for $130. Just add any Fire TV Edition to your cart, then add a third-gen Echo Dot, and presto: The latter is free. Comments $6 at Tidal $999 Turo Lenovo 130-15AST 15.6-inch laptop: $210 (save $90) Boost Mobile Mobile,I’m shocked — shocked! — to learn that stores are turning Labor Day into an excuse to sell stuff. Wait — no, I’m not. As much as I respect the original intent of the holiday (which became official back in 1894), to most of us, it’s just a bonus day off — one that’s blissfully tacked onto a weekend. So, yeah, stores; go ahead, run your sales. I’m listening. Perhaps unsurprisingly, Labor Day doesn’t bring out bargains to compete with the likes of Black Friday (which will be here before you know it), but there are definitely some sales worth your time.For example:We’ve rounded up the best Labor Day mattress deals.We’ve also gathered the best Labor Day laptop deals at Best Buy.The 2019 Vizio P Series Quantum is back under $999.Be sure to check out Amazon’s roughly three dozen Labor Day deals on TVs and audio. Google Express is having a big sale as well, one that includes deals on game consoles, AirPods, iPhones, laptops and more.Below I’ve rounded up a handful of individual items I consider to be the cream of the crop, followed by a handy reference guide to other Labor Day sales. Keep in mind, of course, that products may sell out at any time, even if the sale itself is still running. Note that CNET may get a share of revenue from the sale of the products featured on this page. HP Laptop 15t Value: $520 (save $780) I thought this might be a mistake, but, no, the weirdly named HP Laptop 15t Value is indeed quite the value at this price. Specs include an Intel Core i7 processor, 12GB of RAM, a 256GB solid-state drive and a 15.6-inch display. However, I strongly recommend paying an extra $50 to upgrade that display to FHD (1,920×1,080), because you’re not likely to be happy with the native 1,366×768 resolution. Read Lenovo Smart Clock review See It Comments DJI’s answer to GoPro’s action cameras is rugged little model that’s shockproof, dustproof and waterproof down to 11 meters. It normally runs $350, but this deal drops it to $261 when you apply promo code 19LABOR10 at checkout. Lenovo Smart Clock: $59.99 (save $20) Amazon Recently updated to include digital-photo-frame capabilities, the Lenovo Smart Clock brings Google Assistant goodness to your nightstand. It’s a little smaller than the Amazon Echo Show 5, but also a full $30 less (and tied with Prime Day pricing) during this Best Buy Labor Day sale. MoviePass reportedly froze out subscribers and changed their passwords to keep them off the app. MoviePass MoviePass, the $10-a-month movie subscription service that once dominated the industry, has been hit with financial issues that essentially brought an end to the company as we knew it. It dealt with those issues in-part by changing some users’ passwords to keep them from ordering tickets, according to a Business Insider report this week. MoviePass parent company Helios and Matheson didn’t immediately respond to a request for comment. Because MoviePass’ business model essentially involved paying theaters the full price for customers’ tickets, the company was quickly losing money, according to the report. CEO Mitch Lowe reportedly became frustrated with subscribers who took advantage of the low monthly rate by going to the movies every day, and ordered the company to limit subscriber access before the April 2018 release of Avengers: Infinity War. Lowe called for the passwords for a “small percentage of power users be changed,” which would keep them from going into the MoviePass app and ordering tickets, according to Business Insider.By the end of July 2018, the company was losing around $40 million a month, and on July 26 it ran out of money to put on MoviePass cards, Business Insider says. To get things running again, Helios and Matheson reportedly borrowed $5 million in cash. To deal with the loss of money, MoviePass reportedly made Mission: Impossible – Fallout unavailable for subscribers and froze half of them out on opening weekend, former employees told Business Insider.MoviePass has been wrestling with financial obstacles in the last several months by curbing its offerings. Last year, it reduced its plan to three movies for $10 a month. The company brought back its $9.95 unlimited movie plan in March, albeit with restrictions, before suspending its service indefinitely last month. $999 Chris Monroe/CNET Sarah Tew/CNET Rylo Read Google Home Hub review $520 at HP JBL Soundgear wearable speaker: $90 (save $160) Apple AirPods with Wireless Charging Case: $155 (save $45) TVs Speakers Mobile Accessories Cameras Laptops Automobiles Smart Speakers & Displays $90 at Daily Steals via Google Express MoviePass manages to get more expensive and less useful Angela Lang/CNET $155 at Google Express Mentioned Above Apple iPhone XS (64GB, space gray) Google Nest Hub: $59 (save $70) Read DJI Osmo Action preview $999 Turo is kind of like Uber meets Airbnb: You borrow someone’s car, but you do all the driving. I’ve used it many times and found it a great alternative to traditional car-rental services — in part because you get to choose exactly the vehicle you want (not just, say, “midsize”) and in part because you can often do pickup and dropoff right outside baggage claim.Between now and Sept. 1, the first 300 people to check out can get $30 off any Turo rental with promo code LDW30. 21 $299 at Amazon CNET may get a commission from retail offers. Best laptops for college students: We’ve got an affordable laptop for every student. Best live TV streaming services: Ditch your cable company but keep the live channels and DVR.center_img Read the AirPods review Tidal 3-month family subscription: $5.99 (save $54) $261 at Daily Steals via Google Express Now playing: Watch this: DJI Osmo Action camera: $261 (save $89) The Cheapskate The problem with most entry-level laptops: They come with mechanical hard drives. That makes for a mighty slow Windows experience. This Lenovo model features a 128GB solid-state drive, so it should be pretty quick to boot and load software, even with its basic processor. Plus, it has a DVD-burner! That’s not something you see in many modern laptops, especially at this price. What’s cooler: A snapshot of a firework exploding in front of you, or full 360-degree video of all the fireworks and all the reactions to seeing them? Oooh, ahhh, indeed. At $250, the compact Rylo dual-lens camera is selling for its lowest price yet. And for an extra $50, you can get the bundle that includes the waterproof housing.This deal runs through Sept. 3; it usually costs $500. 1:38 Sarah Tew/CNET Turo: Save $30 on any car rental Apple iPhone XS Share your voice 7 Tags $60 at Best Buy Sarah Tew/CNET $59 at eBay Sprint $210 at Best Buy Free Echo Dot with an Insignia or Toshiba TV (save $50) Preview • iPhone XS is the new $1,000 iPhone X Use promo code 19LABOR10 to get an unusually good deal on JBL’s interesting hybrid product — not quite headphones, and not quite a traditional speaker, but something you wear like neckphones to listen to music on the go. See It Other Labor Day sales you should check out Best Buy: In addition to some pretty solid MacBook deals that have been running for about a week already, Best Buy is offering up to 40% off major appliances like washers, dryers and stoves. There are also gift cards available with the purchase of select appliances. See it at Best BuyDell: Through Aug. 28, Dell is offering an extra 12% off various laptops, desktops and electronics. And check back starting Aug. 29 for a big batch of Labor Day doorbusters. See it at DellGlassesUSA: Aug. 29 – Sept. 3 only, you can save 65% on all frames with promo code labor65. See it at GlassesUSALenovo: The tech company is offering a large assortment of deals and doorbusters through Labor Day, with the promise of up to 56% off certain items — including, at this writing, the IdeaPad 730S laptop for $700 (save $300).See it at LenovoLensabl: Want to keep the frames you already love and paid for? Lensabl lets you mail them in for new lenses, based on your prescription. From now through Sept. 2 only, you can save 20% on the blue light-blocking lens option with promo code BLOCKBLUE. See it at LensablSears: Between now and Sept. 7, you can save up to 40% on appliances (plus an additional 10% if you shop online), up to 60% on mattresses, up to 50% on Craftsman products and more. The store is also offering some fairly hefty cashback bonuses. See it at SearsNote: This post was published previously and is continuously updated with new information.CNET’s Cheapskate scours the web for great deals on tech products and much more. For the latest deals and updates, follow the Cheapskate on Facebook and Twitter. Questions about the Cheapskate blog? Find the answers on our FAQ page, and find more great buys on the CNET Deals page. Share your voice Rylo 5.8K 360 Video Camera: $250 (save $250) Tags Read the Rylo camera preview Sarah Tew/CNET Review • iPhone XS review, updated: A few luxury upgrades over the XR Though not technically a Labor Day sale, it’s happening during Labor Day sale season — and it’s too good not to share. Nationwide Distributors, via Google Express, has just about the best AirPods deal we’ve seen (when you apply promo code ZBEDWZ at checkout). This is for the second-gen AirPods with the wireless charging case. Can’t imagine these will last long at this price, so if you’re interested, act fast. Spotify and most other streaming services rely on compressed audio, which robs the listener of full fidelity. Enter Tidal, the only “major” service that delivers lossless audio — meaning at least on par with CD quality, if not better. Want to see (er, hear) the difference for yourself? Grab this excellent extended trial while you can. It’s just $6 for three months, and it’s good for up to six listeners. See at Turo $999 See at Amazon See it See It Best Buylast_img read more

Lenovo Completes Acquisition Formalities of Motorola from Google

first_imgIt’s official: Lenovo buys Motorola mobilityMotorolaMotorola has announced that the company has officially become a part of the Lenovo family.Under the deal, Lenovo will pay Google, the former owner of Motorola, a total amount of $2.91 billion dollars. The transaction will include 660 million worth cash and 750 million worth stock to be paid by Lenovo. The remaining money worth $1.5 billion will be paid to Google in three years.After the deal, Lenovo will handle the mobility device business part while Google will keep the patents portfolio.Lenovo, the prime laptop and PC manufacturer has not acquired that much of presence in the mobility segment in developed countries. On the other hand, Motorola is quite popular in those countries and is counted as one of the leading Android smartphone manufacturer. Their recent launches, Moto 360 Smartwatch, Moto G, Moto E, Moto X and Droid Turbo, are widely appreciated by the consumers. Even the latest, Nexus 6, the first smartphone featuring Android Lollipop OS is also made by Motorola.With raw Android experience, quick updates, great apps and awesome Google integration, Motorola has risen like a phoenix with good revenues and popularity.In the blog, Motorola mentioned: “We will continue to focus on pure Android experience and fast upgrades, and remain committed to developing technology to solve real consumer problems. And we will continue to develop mobile devices that bring people unprecedented choice, value and quality.”The acquisition of Motorola will add a huge amount of handset sales to Lenovo’s credit and they will hold a 8% share of the global smartphone market, which will lead them to the third best smartphone maker in the global sales, according to a report. Meanwhile, Motorola mobility alone has 5% share in the Indian smartphone market.Rick Osterloh, President and COO will still lead the operation of Motorola out of Chicago.”With an impressive portfolio of smartphones, wearables and PCs, our two companies will be uniquely positioned to push the boundaries of choice and value, and bring exciting new experiences to people everywhere,” Osterloh said.last_img read more

Wipro Q3 earnings in focus after upbeat Infosys results

first_imgWith Infosys’ Q3 earnings beating the Street’s estimates, the focus now turns to Wipro results, which will be released on 18 January.While it is widely expected that Wipro — India’s third largest IT firm — will not be able to spring any surprise in its revenue growth for the December quarter, investors may look for impact of Chennai floods on its income.India’s third largest IT firm Wipro also gave a similar warning about its Q3 earnings following floods in Chennai. The company had said that increase in costs due to deployment of business continuity plans would impact revenues and operating margins for the quarter ended December 2015.The Bengaluru-based IT giant is expected to post a 0.5% growth in dollar revenue for the October-December quarter on a sequential basis, according to an analysts’ poll conducted by CNBC-TV18.Wipro’s dollar revenue stood at $1,831.9 million in the second quarter of the current fiscal year.In constant currency terms, dollar revenue is likely to come at around 1-1.2% against guidance of 0.5-2.5% ($1841-1878 million), due to Chennai floods’ impact witnessed in December last year.Wipro has a headcount of about 22,000 people in its facilities in Chennai.”Revenues from our IT Services business are expected to be in the previously communicated range of $1,841 million to $1,878 million; However, we expect revenues to be in the lower half of the guidance range,” the company had said in the statement.Analysts expect the acquisition of Designit to slightly contribute to Wipro’s revenues in the third quarter. Wipro had acquired Designit, a Denmark-based global strategic design firm, in July last year to improve its income from the emerging digital vertical.In rupee terms, Wipro’s Q3 revenue is expected to increase by 2.7% to Rs 12,371 crore compared to Rs 12,042.8 crore in the September quarter.However, a depreciation in rupee during the quarter is expected to partly offset the impact of Chennai floods on its margins.last_img read more

Oracle ordered to pay HP 3 billion in Itanium case

first_imgA California jury ordered Oracle Corp (ORCL.N) to pay Hewlett-Packard Enterprise Co (HPE.N) $3 billion in damages in a case over HP’s Itanium servers, an Oracle spokeswoman said on Thursday.Oracle said it would appeal the verdict.The Itaniuum processor is made by Intel Inc (INTC.O).Oracle decided to stop developing software for use with HP’s Itanium-based servers in 2011, saying that Intel made it clear that the chip was nearing the end of its life and was shifting its focus to its x86 microprocessor.But HP said it had an agreement with Oracle that support for Itanium would continue, without which the equipment using the chip would become obsolete.In the first phase of trial in 2012, Santa Clara Superior Court Judge James Kleinberg ruled that there had been a contract. The jury on Thursday decided damages.”HP is gratified by the jury’s verdict, which affirms what HP has always known and the evidence overwhelmingly showed,” John Schultz, executive vice president and general counsel of Hewlett Packard Enterprise, said in an e-mailed statement, saying that Oracle’s decision to stop the software development “was a clear breach of contract.”In a statement, Oracle general counsel Dorian Daley said the company had been providing all its latest software for Itanium servers since Kleinberg’s decision.”Now that both trials have concluded, we intend to appeal both today’s ruling and the prior ruling,” Daley said.last_img read more

Farmers agitation sparks milk crisis in Mumbai

Farmers agitation sparks milk crisis in Mumbai

first_imgThousands of milk farmers across Maharashtra launched an agitation for their various demands early on Monday, hitting supply of fresh milk across big and small cities in the state.Scores of milk tankers bound for major cities including Mumbai, Pune, Nagpur, Nashik and others were blocked in different parts of the state, raising the spectre of milk shortage.As the agitation continued, around a dozen milk tankers each from Nashik and Kolhapur were despatched for Mumbai under armed police escorts, while the Opposition Congress and Nationalist Congress Party and others threw their weight behind the agitators.The farmers’ groups, led by Swabhimani Shetkari Sanghatana (SSS) and Maharashtra Kisan Sabha (MKS), are demanding a subsidy of Rs 5 per litre milk, waiver of goods and services tax (GST) on butter and milk powder among others.Tankers laden with lakhs of litres of milk were waylaid and emptied on the roads in Pune, Nashik, Kolhapur, Sangli, Beed, Palghar, Buldana, Washim, Aurangabad and Solapur, while at least one tanker was torched near Amravati en route to the big cities, which are totally dependent on supplies from the rural areas.In other places, activists performed the symbolic ‘dudh-abhishek’ with milk in major temples in Pandharpur, Pune, Beed, Nashik, Ahmednagar and other places to lodge their protest even as the state government warned of strict action.At some places, top leaders like SSS president and MP Raju Shetti and MKS president Ajit Nawale took to the streets to block the milk tankers while several big and small milk cooperatives announced support to the farmers’ agitation.”The state government has fixed the procurement price of Rs 27 per litre but the farmers get barely Rs 17 per litre. We are demanding a direct subsidy of Rs 5 per litre to the farmers, as provided in Goa, Karnataka and Kerala.”With a drop in the rates of skimmed milk powder, even the milk cooperatives are facing a tough time,” Shetti told the media.Nawale said the government’s announcement of Rs 50 per kg subsidy for milk powder may not benefit the farmers since the prices of milk powder have come down in the international market, but would be a boon to private companies which convert milk into powder.As the issue was taken up in the Maharashtra Legislature in Nagpur, animal husbandry and dairy development minister Mahadev Jankar assured that the cities would not suffer any milk shortages.He said that Mumbai, which requires over seven million litres fresh milk daily, has adequate stocks of 15 days. Most urban centres together account for over 10 million litres, with Pune and surroundings needing 1.3 million daily.”We are trying to resolve the issue. If anybody attempts to break the law, they will be dealt with sternly,” Jankar warned the farmers, and later said the government was prepared to give Rs 3 per litre subsidy.Minister of State for Cooperation Subhash Deshmukh accused the protesting leaders of deliberately “misleading” milk producers with the agitation.”Their sole objective seems to be to embarrass the state government and harass the milk producers,” he said.On reports that the government planned to “import” milk from Gujarat and Karnataka to meet the requirements, Shetti shot back that it was a ploy to break the farmers agitation and they would launch a satyagraha against the state’s move.According to official figures, Maharashtra has approximately 15,000 cooperative dairy societies, 85 cooperative dairy unions, 98 milk processing plans, 156 chilling centres and 192 cold storages including 167 in the private sector.last_img read more